Incorrect administration of insulin (e.g., too little, too much, or at wrong times) can result in transient and serious hypo- and hyperglycemia, wide glycemic excursions, and diabetic ketoacidosis. Special care must be taken to ensure that correct dose of insulin is administered. A report of cases in which providers asked patients to demonstrate his or her insulin injection technique identified serious flaws in insulin selfadministration. In one case, a patient was not properly using an insulin pen and so was unaware that she was not getting any insulin at all. In addition, the recommended practice of priming the pen before each injection to remove air from the needle reduces the insulin dose to be administered. There is a need to accurately confirm the dose of insulin injected, thus providing more reliable and accurate treatment.