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InSTENT Connection

Submitted by acecilia on

Using staples and/ or stitches to create GI anastomoses often results in leaking of GI content, which leads to severe health issues, including infection, sepsis, and death. Among the approximately 700,000 GI surgeries performed worldwide involving anastomoses on colon cancer patients, leaking can occur in up to 30% of patients, and mortality rates from these leaks can be as high as 39%, placing a severe emotional and financial burden on surgical patients worldwide. To address this, we partnered with a surgeon at UW Medicine to design a bioresorbable stent and compressive band system that can be used to create these surgical connections without the use of staples or stitches. The stent will be placed inside and between the two pieces of the colon that need to be surgically connected to each other. The barbs on the exterior of the stent will prevent the migration of the device. Once the stent is implanted, the compressive band will be secured outside the pieced of the overlapped intestine, centered at the anastomotic site. The band will clamp the intestine ends to the stent and act as an additional barrier against leaking of the GI content from the surgical site. Once the wound has healed naturally, the internal stent and compressive band will degrade and be resorbed by the body over time, leaving only the new tissue growth over the surgical site. 

 

Student team
Jimmy Ye
Gillian Pereira
Brandon Lou
Clara Black
Evan Ross
Mentoring team
James Park, MD (UW Surgery)
Eric Seibel, PhD (ME, ECE, BioE, Oral Health Science)
West Long, MBA
Year
Continuing project
Yes